Scientists have reported in Nature (March 26, 2009 issue) that a protein called caspase 8 plays a critical role in the healing of wounds in laboratory mice. Caspase 8 is deficient in humans with eczema, but produced in excess amounts by diabetics.
The researchers say their discovery may explain why many diabetics lack a normal wound response and suffer severe complications from minor cuts and scrapes, and why those with eczema exhibit a chronic inflammation of the skin that compromises its protective function.
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